INDIANAPOLIS — Jaime Jaquez Jr. scored 17 points, hitting two big jumpers early in overtime, and No. 11 seed UCLA held on after Alabama’s Alex Reese drained a buzzer-beating 3-pointer at the end of regulation to beat the second-seeded Crimson Tide 88-78 in a Sweet 16 showdown Sunday night.

After star guard Johnny Juzang fouled out late in regulation, Jaquez and David Singleton took control in overtime. Jaquez curled in a jumper to make it 74-68, then drilled a 3-pointer for a 77-70 lead. Singleton’s free throws made it 79-70 with under a minute to go, and all UCLA (21-9) had to do was put the game away from the foul line.

After beating Michigan State in overtime just to escape the First Four, the unheralded Bruins are headed to the Elite Eight for the first time since 2008. They’ll face top-seeded Michigan on Tuesday night for a spot in the Final Four.

UCLA thought it had the game won in regulation when Cody Riley’s lay-in made it 63-62 with 14 seconds left, and Herbert Jones – a 75% foul shooter for Alabama – missed both of his attempts with 6 seconds left.

Singleton was fouled and hit two free throws for UCLA, pushing the lead to 65-62 with 4 seconds to go. But that still gave the Crimson Tide enough time to find Reese, whose tying 3-pointer splashed just before the buzzer.

Jules Bernard also scored 17 points, Singleton had 15, and Juzang and Tyger Campbell added 13 apiece as the Bruins gave Coach Mick Cronin his first trip to a regional final in 18 years as a college head coach.

Jahvon Quinerly scored 20 points and John Petty Jr. had 16 for the Crimson Tide (26-7), who have lost eight of their nine games in the Sweet 16.

(1) MICHIGAN 76, (4) FLORIDA STATE 58: Hunter Dickinson scored 14 points and top-seeded Michigan (23-4) took the inside route to the Elite Eight, pounding away in the paint for a takedown of surprisingly helpless Florida State (18-7).

Franz Wagner had 13 points and 10 rebounds for the Wolverines, who scored their first 30 points of the second half from close range.

Badly off target most of the night, Florida State didn’t eclipse the 20-point mark until M.J. Walker (10 points) hit a jumper with 27 seconds left in the first half.

Walker, the team’s leading scorer this season, rolled his ankle at the 14-minute mark of the second half. By the time he came back eight minutes later, the Seminoles trailed by 19.

WEST REGIONAL

(1) GONZAGA 83, (5) CREIGHTON 65: Drew Timme scored 22 points and top-seeded Gonzaga (29-0) did against Creighton (22-9) what it’s done throughout this unblemished season, rolling past the fifth-seeded Bluejays with versatile offense and efficient defense.

Andrew Nembhard added 17 points for the Bulldogs, who have won a school-record 33 consecutive games and extended their Division I record to 26 straight double-digit wins.

Gonzaga did it this time on a quiet day for star Jalen Suggs, who finished with nine points. The Bulldogs methodically built a 10-point halftime lead and pushed ahead by 20 on Suggs’ layup with 11:22 left.

Gonzaga is three wins away from becoming the first undefeated national champion since Indiana in 1976.

“I don’t think we have peaked,” said Nembhard. “I think, as I said earlier, we can always get better. We can always work on our stuff. So I think we’re getting close, and we need to squeeze out that five percent that we talked about.”

The Bulldogs will face sixth-seeded USC in the West Regional final on Tuesday.

Marcus Zegarowski scored 19 points to lead the Bluejays.

As they have many times this season, the Zags led wire to wire.

Joel Ayayi finished with 13 points and eight rebounds, and Corey Kispert had 12 points for Gonzaga, which shot 59.6% from the field.

“I’m just telling you: We’re not hung up on the undefeated thing at all,” Coach Mark Few said. “We’ve got to go undefeated from here on out. We’ve got to go 3-0 if we want to win the championship, which (has) been our goal all along. But nobody’s talking about the overall undefeated thing at all.”

(6) USC 82, (7) OREGON 68: Isaiah White scored 22 points and Southern California shut down Oregon’s potent offense to reach the Elite Eight for the first time in 20 years.

The Trojans (25-7) clipped the high-flying Ducks with their length on the perimeter and 7-footer Evan Mobley in the middle. Offensively, the region’s No. 6 seed bobbed and weaved through the holes in Oregon’s defense, shooting 57% overall and 10 of 17 from 3.

The all-around domination put three Pac-12 teams in the Elite Eight for the first time since 2001.

Oregon certainly had no answer for the long-armed Trojans.

The seventh-seed Ducks (21-7) floundered against USC’s zone, unable to find holes or get much of anything to drop over it until a late rally that came up short. The Pac-12’s best 3-point shooting team (38%) went 5 of 21 from behind the arc.

Eugene Omoruyi had 28 points and 10 rebounds, and Chris Duarte scored 21 points for the Ducks.